25-MAY-2024 6:10

LYMPH ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support
STUDY R
E
G
O
P
E
N
ARM ACCR.
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
SWOG S1608-FL, TGR-1202/Lenalidomide/CHOP or Benda +Ob 1 Y 1 TGR-1202 + Obinutuzumab 95 26 0 0 0 0 0 01/23/2018 189 71
        2 Lenalidomide + Obinutuzumab   27 2 0 0 0 0      
        3 CHOP + Obinutuzumab   12 1 0 0 0 0      
        4 Bendamustine + Obinutuzumab   12 1 0 0 0 0      
            77 4 0 0 0 0      
 
  S1918-DLBCL, Adv, Age 75+, CC-486 +/- R-miniCHOP 1 Y 1 CC-486 + R-miniCHOP 422 51 21 14 6 2 0 05/25/2021 173 70
        2 R-miniCHOP   50 24 12 6 3 0      
            101 45 26 12 5 0      
 
  S2114-NHL, Rel/Ref, CD19 CAR-T +/- Consolidation 1 Y 0 CD19 CAR T-cell Therapy 396 49 49 27 17 8 2 06/12/2023 121 39
            49 49 27 17 8 2      
 
    2 Y 1 Mosunetuzumab   2 2 1 0 0 0 06/12/2023    
        2 Polatuzumab   2 2 2 0 0 0      
        3 Mosunetuzumab + Polatuzumab   3 3 1 1 1 0      
        4 Observation   2 2 1 0 0 0      
            9 9 5 1 1 0      
 
  S2207-LBCL, Transplant Inelig, Targeted Tx + Tafa 1 Y 1 Tazemetostat (Arm 1) Dose Level 1 227 5 5 4 4 3 2 09/26/2023 95 33
        4 Zanubrutinib (Arm 3) Dose Level 1   10 10 7 6 0 0      
            15 15 11 10 3 2      
 
Yes A051902-PTCL,CHO(E)PvCC-486-CHO(E)PvDuvelisib-CHO(E)P 1 E Total Registrations   4 4 3 3 0 0 10/14/2023 159 71
            4 4 3 3 0 0      
 
  A052101-Lymph, Stg I-IV, Cont v Intermittent Zanub 1 E Total Registrations   5 5 5 3 0 0 01/03/2024 185 70
            5 5 5 3 0 0      
 
    2 E Total Registrations   1 1 1 0 0 0 01/03/2024    
            1 1 1 0 0 0      
 
  AHOD2131-cHL,StgI-II,StdTherapyvImmuno-oncologyTherapy 1 E Total Registrations   17 17 8 4 0 0 08/15/2023 170 106
            17 17 8 4 0 0      
 
    2 E Total Registrations   13 13 10 2 0 0 08/15/2023    
            13 13 10 2 0 0      
 
  E4412-HD, RR, Ipilimumab +Nivo +Brentuximab Vedotin 1 E Total Registrations   20 0 0 0 0 0 04/17/2019 89 56
            20 0 0 0 0 0      
 
  EA4151-Lymph, AHCT +/-Ritux, MRD Neg 0 E Total Registrations   168 23 16 12 1 1 04/03/2018 226 81
            168 23 16 12 1 1      
 
    1 E Total Registrations   130 15 10 9 3 0 04/03/2018    
            130 15 10 9 3 0      
 
No A051701-LYMPH, MYC/BC2 DHL&DEL, R-chemo+/-Venetoclax 1 T Total Registrations   34 0 0 0 0 0 01/02/2020    
            34 0 0 0 0 0      
 
  ANHL1931-PMBCL, Chemo-Immunotherapy +/- Nivo 1 E Total Registrations   22 13 7 4 2 0 02/28/2022 216 105
            22 13 7 4 2 0      
 

25-MAY-2024 6:10

LYMPH Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs
# of
CURR
IRBs
S2114 NHL, Rel/Ref, CD19 CAR-T +/- Consolidation 3 Crossover 23-Feb-23 121 39