14-AUG-2026 6:11

Lung-MAP ACCRUAL REPORT

  O
P
E
N
ACCR
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
LUNGMAP Screening Protocol Registrations
Total     4081 378 180 85 28 4 02/06/2019 474 184
Screened at PD     1544 245 129 57 18 4      
Pre-Screened prior to PD     2511 116 45 23 8 0      
Treatment-naive     26 17 6 5 2 0      
ctDNA Specimen Submission     315 0 0 0 0 0      
Re-analysis Requests     537 29 13 4 2 1      
 
Sub-Study Assignments
LUNGMAP Sub-Study Assignments     2247 307 158 73 22 6      
Screened at PD     1314 246 132 60 19 5      
Pre-Screened prior to PD     849 41 18 7 1 1      
Treatment-naive     26 17 6 5 2 0      
After PD on a Lung_MAP Sub-Study     58 3 2 1 0 0      
 
Sub-Study Assignments (open studies only)
S1800E     433 266 139 60 19 6      
S1900G     41 10 7 6 0 0      
S1900J     18 6 3 0 0 0      
S1900K     44 24 8 6 2 0      
S1900N     1 1 1 1 1 0      
 
Sub-Study Registrations
LUNGMAP Sub-Study Registrations     664 144 77 43 15 3      
Initial sub-study registrations     651 143 76 42 15 3      
Subsequent sub-study registrations     13 1 1 1 0 0      
 
Patients Registered to a Sub-Study (open studies only)
S1800E: Non-Match: Docetaxel + Ramu +/- Cemiplimab   378 129 118 67 36 14 3 05/22/2025 358 118
Docetaxel plus Ramucirumab Y   67 61 36 18 8 2      
Cemiplimab plus Docetaxel and Ramucirumab Y   62 57 31 18 6 1      
S1900G: EGFR-Mut, MET-Amp: Capmat + Osimert +/- Ramu   44 28 7 4 3 1 0 05/05/2023 336 107
Capmatinib + Osimertinib + Ramucirumab Y   16 5 2 2 1 0      
Capmatinib + Osimertinib Y   12 2 2 1 0 0      
S1900J: MET Amplification: Amivantamab Hyaluronidase   88 4 2 1 0 0 0 11/19/2024 280 86
Amivantamab Hyaluronidase Y   4 2 1 0 0 0      
S1900K: MET Exon 14: Tepotinib +/- Ramucirumab   56 29 17 5 4 0 0 08/08/2024 273 90
Tepotinib + Ramucirumab Y   20 12 4 4 0 0      
Tepotinib Y   9 5 1 0 0 0      
 

14-AUG-2026 6:11

Lung-MAP Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs
# of
CURR
IRBs
S1900N AGAs: SG alone, I alone, or SG + I 1 Randomization 03-Aug-26 85 18