O P E N |
ACCR GOAL |
TOTAL REGS. |
REGS. LAST 12 Month |
REGS. LAST 6 Month |
REGS. LAST 3 Month |
REGS. LAST 30 DAYS |
REGS. LAST 7 DAYS |
DATE OF FIRST REG. |
# of ACT. INSTs |
# of CURR IRBs |
|
---|---|---|---|---|---|---|---|---|---|---|---|
LUNGMAP Screening Protocol Registrations | |||||||||||
Total | 3434 | 311 | 158 | 84 | 33 | 6 | 02/06/2019 | 419 | 178 | ||
Screened at PD | 1212 | 70 | 26 | 14 | 2 | 0 | |||||
Pre-Screened prior to PD | 2222 | 241 | 132 | 70 | 31 | 6 | |||||
ctDNA Specimen Submission | 315 | 0 | 0 | 0 | 0 | 0 | |||||
Re-analysis Requests | 465 | 105 | 54 | 27 | 12 | 2 | |||||
Sub-Study Assignments | |||||||||||
LUNGMAP Sub-Study Assignments | 1729 | 58 | 25 | 13 | 4 | 1 | |||||
Screened at PD | 978 | 33 | 13 | 6 | 2 | 0 | |||||
Pre-Screened prior to PD | 699 | 25 | 12 | 7 | 2 | 1 | |||||
After PD on a Lung_MAP Sub-Study | 52 | 0 | 0 | 0 | 0 | 0 | |||||
Sub-Study Assignments (open studies only) | |||||||||||
S1900E | 240 | 39 | 15 | 8 | 2 | 1 | |||||
S1900G | 20 | 15 | 6 | 3 | 1 | 0 | |||||
S1900K | 4 | 4 | 4 | 2 | 1 | 0 | |||||
Sub-Study Registrations | |||||||||||
LUNGMAP Sub-Study Registrations | 484 | 31 | 11 | 5 | 2 | 0 | |||||
Initial sub-study registrations | 472 | 31 | 11 | 5 | 2 | 0 | |||||
Subsequent sub-study registrations | 12 | 0 | 0 | 0 | 0 | 0 | |||||
Patients Registered to a Sub-Study (open studies only) | |||||||||||
S1900E: KRAS G12C: Sotorasib (AMG 510) | 116 | 115 | 20 | 6 | 3 | 1 | 0 | 04/16/2021 | 315 | 127 | |
Cohort 1: TP53 | N | 48 | 6 | 0 | 0 | 0 | 0 | ||||
Cohort 2: STK11 | Y | 28 | 8 | 4 | 2 | 0 | 0 | ||||
Cohort 3: All Others | Y | 39 | 6 | 2 | 1 | 1 | 0 | ||||
S1900G: EGFR-Mut, MET-Amp: Capmat + Osimert +/- Ramu | 66 | 13 | 11 | 5 | 2 | 1 | 0 | 05/05/2023 | 264 | 100 | |
Capmatinib + Osimertinib + Ramucirumab | Y | 6 | 5 | 3 | 2 | 1 | 0 | ||||
Capmatinib + Osimertinib | Y | 7 | 6 | 2 | 0 | 0 | 0 | ||||
Study | Registration/Phase | Open Date | # of ACT. INSTs |
# of CURR IRBs |
---|---|---|---|---|
S1900K MET Exon 14: Tepotinib +/- Ramucirumab | 1 Randomization | 18-Dec-23 | 217 | 84 |