05-JUL-2022 6:10

Lung-MAP ACCRUAL REPORT

  ACCR
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
LUNGMAP Screening Protocol Registrations
Total   2567 473 291 176 50 9
Screened at PD   943 128 87 56 16 2
Pre-Screened prior to PD   1624 345 204 120 34 7
ctDNA Specimen Submission   284 26 16 11 4 0
Re-analysis Requests   180 163 110 57 11 3
 
Sub-Study Assignments
LUNGMAP Sub-Study Assignments   1369 387 346 77 20 5
Screened at PD   785 159 131 48 8 3
Pre-Screened prior to PD   537 207 194 28 12 2
After PD on a Lung_MAP Sub-Study   47 21 21 1 0 0
 
Sub-Study Assignments (open studies only)
S1800D   326 326 326 63 16 5
S1900E   136 76 35 14 4 0
 
Sub-Study Registrations
LUNGMAP Sub-Study Registrations   365 72 43 30 9 1
Initial sub-study registrations   355 71 42 29 9 1
Subsequent sub-study registrations   10 1 1 1 0 0
 
Patients Registered to a Sub-Study (open studies only)
S1800D: Non-Match: N-803 + Pembro vs SoC 478 25 25 25 22 7 0
Primary Resistance   2 2 2 1 1 0
Acquired Resistance   23 23 23 21 6 0
S1900E: KRAS G12C: Sotorasib (AMG 510) 116 66 47 18 8 2 1
Cohort 1: TP53   30 23 10 6 2 1
Cohort 2: STK11   15 8 4 2 0 0
Cohort 3: All Others   21 16 4 0 0 0