SAS Output

25-APR-2019 6:10

MELAN ACCRUAL REPORT - Open and Recently Closed Studies

The REPORT Procedure

Detailed and/or summarized report

Table 1

SWOG/
Support
STUDY R
E
G
O
P
E
N
ARM ACCR.
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
SWOG S1320-Adv, BRAF mut, Inter v Contin 1 N 1 Lead-in Continuous Dosing 248 249 36 24 12 6 0 09/19/2014 233 96
            249 36 24 12 6 0      
 
    2 Y 2 Continuous Dosing 216 103 17 8 4 1 0 09/19/2014    
        3 Intermittent Dosing   101 18 11 7 3 0      
            204 35 19 11 4 0      
 
  S1512-Melan, Adv, Desmoplastic, MK-3475 (pembro) 1 Y 1 MK-3475 (pembrolizumab) 77 22 15 5 4 1 0 02/06/2017 91 41
            22 15 5 4 1 0      
 
  S1607-MELAN, Adv, T-VEC, MK-3475 1 Y 1 T-VEC + MK-3475(pembrolizumab) 64 16 16 10 5 3 1 06/05/2018 56 26
            16 16 10 5 3 1      
 
  S1616-MELAN, Adv, Ipilimumab Nivolumab 1 Y 1 Ipilimumab 94 10 8 2 2 1 0 10/23/2017 209 87
        2 Nivolumab + Ipilimumab   28 22 11 7 3 0      
            38 30 13 9 4 0      
 
  S1801-Melan, Adv, Adj vs Neoadj Pembrolizumab 1 Y 1 Adjuvant Arm 556 5 5 5 5 3 1 02/15/2019 192 77
        2 Neoadjuvant Pembrolizumab   2 2 2 2 2 1      
            7 7 7 7 5 2      
 
    2 Y 3 Surgery 556 3 3 3 3 1 0 02/15/2019    
            3 3 3 3 1 0      
 
    3 Y 4 Post-Surgery Pembro 556 1 1 1 1 0 0 02/15/2019    
            1 1 1 1 0 0      
 
Yes EA6134-Adv, BRAF mut, D+T/Ipi+Niv vs Ipi+Niv/D+T 1 E Total Registrations   35 9 5 5 0 0 11/03/2015 361 143
            35 9 5 5 0 0      
 
    2 E Total Registrations   13 6 1 1 1 0 11/03/2015    
            13 6 1 1 1 0      
 
  EA6141-Melan, Avd, Nivolumab+Ipi Sargmostim 1 E Total Registrations   36 0 0 0 0 0 03/25/2016 219 93
            36 0 0 0 0 0      
 

25-APR-2019 6:10

MELAN Recently Closed Studies Accrual Report

The REPORT Procedure

Detailed and/or summarized report

Table 1

OPEN Study Date
Closed
Reg. Arm Total
Regs
Regs
Last
30 Days
Regs
Last
7 Days
N S1320-Adv, BRAF mut, Inter v Contin 19-Apr-19 1 1 Lead-in Continuous Dosing 249 6 0