06-DEC-2025 6:10

LYMPH ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support		 STUDY R
E
G		 O
P
E
N		 ARM ACCR.
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
SWOG S1918-DLBCL, Adv, Age 75+, CC-486 +/- R-miniCHOP 1 T 1 CC-486 + R-miniCHOP 422 69 6 0 0 0 0 05/25/2021 193 60
        2 R-miniCHOP   67 7 0 0 0 0      
            136 13 0 0 0 0      
 
  S2114-NHL, Rel/Ref, CD19 CAR-T +/- Consolidation 1 Y 0 CD19 CAR T-cell Therapy 396 177 86 36 24 7 2 06/12/2023 103 39
            177 86 36 24 7 2      
 
    2 Y 1 Mosunetuzumab   9 5 1 0 0 0 06/12/2023    
        2 Polatuzumab   10 6 2 2 0 0      
        3 Mosunetuzumab + Polatuzumab   9 5 2 1 1 0      
        4 Observation   10 6 4 2 2 0      
            38 22 9 5 3 0      
 
    3 Y 5 Mosunetuzumab + Polatuzumab   4 3 1 1 0 0 06/12/2023    
            4 3 1 1 0 0      
 
  S2207-LBCL, Transplant Inelig, Targeted Tx + Tafa 1 Y 1 Tazemetostat (Arm 1) Dose Level 1 241 7 0 0 0 0 0 09/26/2023 148 42
        10 Tazemetostat (Arm 1) Dose Level 1   6 6 6 4 0 0      
        13 Zanubrutinib (Arm 3) Dose Level 2   1 1 1 1 0 0      
        4 Zanubrutinib (Arm 3) Dose Level 1   10 0 0 0 0 0      
        5 Zanubrutinib (Arm 3) Dose Level 2   10 0 0 0 0 0      
            34 7 7 5 0 0      
 
  S2308-FL, LTB, Mosunetuzumab vs Rituximab 1 Y 1 Rituximab 600 111 107 56 27 10 2 10/23/2024 272 90
        2 Mosunetuzumab   111 106 55 27 7 0      
            222 213 111 54 17 2      
 
Yes A051902-PTCL,CHO(E)PvCC-486-CHO(E)PvDuvelisib-CHO(E)P 1 E Total Registrations   19 8 2 0 0 0 10/14/2023 193 77
            19 8 2 0 0 0      
 
  A052101-Lymph, Stg I-IV, Cont v Intermittent Zanub 1 E Total Registrations   26 14 8 6 2 1 01/03/2024 212 74
            26 14 8 6 2 1      
 
    2 E Total Registrations   12 9 3 1 0 0 01/03/2024    
            12 9 3 1 0 0      
 
  AHOD2131-cHL,StgI-II,StdTherapyvImmuno-oncologyTherapy 1 E Total Registrations   80 49 25 14 7 3 08/15/2023 281 126
            80 49 25 14 7 3      
 
    2 E Total Registrations   68 44 23 9 4 2 08/15/2023    
            68 44 23 9 4 2      
 
No EA4232-Lymph, Peri T Cell, Auto Stem 1 E Total Registrations   1 1 1 1 0 0 09/15/2025 31 6
            1 1 1 1 0 0