07-AUG-2025 6:10

LYMPH ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support		 STUDY R
E
G		 O
P
E
N		 ARM ACCR.
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
SWOG S1918-DLBCL, Adv, Age 75+, CC-486 +/- R-miniCHOP 1 T 1 CC-486 + R-miniCHOP 422 69 12 4 0 0 0 05/25/2021 177 65
        2 R-miniCHOP   67 11 4 0 0 0      
            136 23 8 0 0 0      
 
  S2114-NHL, Rel/Ref, CD19 CAR-T +/- Consolidation 1 Y 0 CD19 CAR T-cell Therapy 396 150 84 42 17 7 0 06/12/2023 100 43
            150 84 42 17 7 0      
 
    2 Y 1 Mosunetuzumab   8 4 3 0 0 0 06/12/2023    
        2 Polatuzumab   8 5 2 1 0 0      
        3 Mosunetuzumab + Polatuzumab   8 4 3 1 0 0      
        4 Observation   8 5 2 2 1 1      
            32 18 10 4 1 1      
 
    3 Y 5 Mosunetuzumab + Polatuzumab   3 3 2 0 0 0 06/12/2023    
            3 3 2 0 0 0      
 
  S2207-LBCL, Transplant Inelig, Targeted Tx + Tafa 1 Y 1 Tazemetostat (Arm 1) Dose Level 1 241 7 0 0 0 0 0 09/26/2023 119 34
        4 Zanubrutinib (Arm 3) Dose Level 1   10 0 0 0 0 0      
        5 Zanubrutinib (Arm 3) Dose Level 2   10 5 0 0 0 0      
            27 5 0 0 0 0      
 
  S2308-FL, LTB, Mosunetuzumab vs Rituximab 1 Y 1 Rituximab 600 72 72 59 31 7 2 10/23/2024 252 82
        2 Mosunetuzumab   73 73 59 31 10 2      
            145 145 118 62 17 4      
 
Yes A051902-PTCL,CHO(E)PvCC-486-CHO(E)PvDuvelisib-CHO(E)P 1 E Total Registrations   19 10 6 3 2 0 10/14/2023 179 78
            19 10 6 3 2 0      
 
  A052101-Lymph, Stg I-IV, Cont v Intermittent Zanub 1 E Total Registrations   19 11 3 2 0 0 01/03/2024 200 72
            19 11 3 2 0 0      
 
    2 E Total Registrations   11 10 6 2 1 1 01/03/2024    
            11 10 6 2 1 1      
 
  AHOD2131-cHL,StgI-II,StdTherapyvImmuno-oncologyTherapy 1 E Total Registrations   65 44 30 14 3 1 08/15/2023 284 132
            65 44 30 14 3 1      
 
    2 E Total Registrations   54 39 26 17 6 3 08/15/2023    
            54 39 26 17 6 3