29-JUL-2026 6:10

Lung-MAP ACCRUAL REPORT

  O
P
E
N		 ACCR
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
LUNGMAP Screening Protocol Registrations
Total     4067 376 187 83 32 3 02/06/2019 474 184
Screened at PD     1534 239 132 56 23 2      
Pre-Screened prior to PD     2508 119 48 23 8 1      
Treatment-naive     25 18 7 4 1 0      
ctDNA Specimen Submission     315 0 0 0 0 0      
Re-analysis Requests     535 27 13 3 1 0      
 
Sub-Study Assignments
LUNGMAP Sub-Study Assignments     2234 301 158 74 26 6      
Screened at PD     1303 238 132 59 21 5      
Pre-Screened prior to PD     848 42 17 10 4 0      
Treatment-naive     25 18 7 4 1 1      
After PD on a Lung_MAP Sub-Study     58 3 2 1 0 0      
 
Sub-Study Assignments (open studies only)
S1800E     420 258 137 61 20 3      
S1900G     41 10 7 6 3 0      
S1900J     18 6 3 0 0 0      
S1900K     43 25 9 5 1 1      
S1900N     2 2 2 2 2 2      
 
Sub-Study Registrations
LUNGMAP Sub-Study Registrations     655 141 78 35 11 2      
Initial sub-study registrations     642 140 77 34 10 2      
Subsequent sub-study registrations     13 1 1 1 1 0      
 
Patients Registered to a Sub-Study (open studies only)
S1800E: Non-Match: Docetaxel + Ramu +/- Cemiplimab   378 120 114 65 28 10 2 05/22/2025 350 117
Docetaxel plus Ramucirumab Y   62 59 33 14 4 2      
Cemiplimab plus Docetaxel and Ramucirumab Y   58 55 32 14 6 0      
S1900G: EGFR-Mut, MET-Amp: Capmat + Osimert +/- Ramu   44 28 7 4 3 1 0 05/05/2023 336 107
Capmatinib + Osimertinib + Ramucirumab Y   16 5 2 2 1 0      
Capmatinib + Osimertinib Y   12 2 2 1 0 0      
S1900J: MET Amplification: Amivantamab Hyaluronidase   88 4 2 1 0 0 0 11/19/2024 280 86
Amivantamab Hyaluronidase Y   4 2 1 0 0 0      
S1900K: MET Exon 14: Tepotinib +/- Ramucirumab   56 29 18 8 4 0 0 08/08/2024 273 90
Tepotinib + Ramucirumab Y   20 12 7 4 0 0      
Tepotinib Y   9 6 1 0 0 0      
 

29-JUL-2026 6:10

Lung-MAP Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs		 # of
CURR
IRBs
S1900N AGAs: SG alone, I alone, or SG + I 1 Randomization 27-Jul-26