| O P E N |
ACCR GOAL |
TOTAL REGS. |
REGS. LAST 12 Month |
REGS. LAST 6 Month |
REGS. LAST 3 Month |
REGS. LAST 30 DAYS |
REGS. LAST 7 DAYS |
DATE OF FIRST REG. |
# of ACT. INSTs |
# of CURR IRBs |
|
|---|---|---|---|---|---|---|---|---|---|---|---|
| LUNGMAP Screening Protocol Registrations | |||||||||||
| Total | 4029 | 376 | 181 | 86 | 27 | 4 | 02/06/2019 | 471 | 184 | ||
| Screened at PD | 1508 | 235 | 123 | 60 | 16 | 3 | |||||
| Pre-Screened prior to PD | 2497 | 123 | 48 | 22 | 8 | 1 | |||||
| Treatment-naive | 24 | 18 | 10 | 4 | 3 | 0 | |||||
| ctDNA Specimen Submission | 315 | 0 | 0 | 0 | 0 | 0 | |||||
| Re-analysis Requests | 533 | 28 | 13 | 4 | 1 | 0 | |||||
| Sub-Study Assignments | |||||||||||
| LUNGMAP Sub-Study Assignments | 2204 | 300 | 158 | 83 | 27 | 5 | |||||
| Screened at PD | 1281 | 234 | 129 | 70 | 23 | 5 | |||||
| Pre-Screened prior to PD | 842 | 46 | 18 | 8 | 1 | 0 | |||||
| Treatment-naive | 24 | 18 | 10 | 4 | 3 | 0 | |||||
| After PD on a Lung_MAP Sub-Study | 57 | 2 | 1 | 1 | 0 | 0 | |||||
| Sub-Study Assignments (open studies only) | |||||||||||
| S1800E | 395 | 259 | 134 | 71 | 20 | 3 | |||||
| S1900G | 38 | 8 | 5 | 4 | 2 | 1 | |||||
| S1900J | 19 | 7 | 4 | 2 | 1 | 1 | |||||
| S1900K | 42 | 26 | 15 | 6 | 4 | 0 | |||||
| Sub-Study Registrations | |||||||||||
| LUNGMAP Sub-Study Registrations | 639 | 132 | 76 | 42 | 16 | 3 | |||||
| Initial sub-study registrations | 627 | 132 | 76 | 42 | 16 | 3 | |||||
| Subsequent sub-study registrations | 12 | 0 | 0 | 0 | 0 | 0 | |||||
| Patients Registered to a Sub-Study (open studies only) | |||||||||||
| S1800E: Non-Match: Docetaxel + Ramu +/- Cemiplimab | 378 | 106 | 104 | 60 | 35 | 12 | 2 | 05/22/2025 | 349 | 115 | |
| Docetaxel plus Ramucirumab | Y | 55 | 54 | 30 | 19 | 6 | 1 | ||||
| Cemiplimab plus Docetaxel and Ramucirumab | Y | 51 | 50 | 30 | 16 | 6 | 1 | ||||
| S1900G: EGFR-Mut, MET-Amp: Capmat + Osimert +/- Ramu | 44 | 27 | 7 | 4 | 3 | 1 | 1 | 05/05/2023 | 338 | 107 | |
| Capmatinib + Osimertinib + Ramucirumab | Y | 15 | 5 | 2 | 1 | 1 | 1 | ||||
| Capmatinib + Osimertinib | Y | 12 | 2 | 2 | 2 | 0 | 0 | ||||
| S1900J: MET Amplification: Amivantamab Hyaluronidase | 88 | 4 | 2 | 1 | 0 | 0 | 0 | 11/19/2024 | 283 | 84 | |
| Amivantamab Hyaluronidase | Y | 4 | 2 | 1 | 0 | 0 | 0 | ||||
| S1900K: MET Exon 14: Tepotinib +/- Ramucirumab | 56 | 28 | 19 | 11 | 4 | 3 | 0 | 08/08/2024 | 270 | 89 | |
| Tepotinib + Ramucirumab | Y | 19 | 12 | 9 | 3 | 3 | 0 | ||||
| Tepotinib | Y | 9 | 7 | 2 | 1 | 0 | 0 | ||||