| O P E N |
ACCR GOAL |
TOTAL REGS. |
REGS. LAST 12 Month |
REGS. LAST 6 Month |
REGS. LAST 3 Month |
REGS. LAST 30 DAYS |
REGS. LAST 7 DAYS |
DATE OF FIRST REG. |
# of ACT. INSTs |
# of CURR IRBs |
|
|---|---|---|---|---|---|---|---|---|---|---|---|
| LUNGMAP Screening Protocol Registrations | |||||||||||
| Total | 3929 | 345 | 194 | 96 | 36 | 9 | 02/06/2019 | 472 | 182 | ||
| Screened at PD | 1436 | 186 | 119 | 59 | 26 | 6 | |||||
| Pre-Screened prior to PD | 2473 | 139 | 65 | 31 | 9 | 3 | |||||
| Treatment-naive | 20 | 20 | 10 | 6 | 1 | 0 | |||||
| ctDNA Specimen Submission | 315 | 0 | 0 | 0 | 0 | 0 | |||||
| Re-analysis Requests | 528 | 30 | 16 | 9 | 6 | 1 | |||||
| Sub-Study Assignments | |||||||||||
| LUNGMAP Sub-Study Assignments | 2112 | 357 | 144 | 73 | 29 | 5 | |||||
| Screened at PD | 1204 | 211 | 114 | 58 | 26 | 5 | |||||
| Pre-Screened prior to PD | 832 | 122 | 19 | 8 | 1 | 0 | |||||
| Treatment-naive | 20 | 20 | 10 | 7 | 2 | 0 | |||||
| After PD on a Lung_MAP Sub-Study | 56 | 4 | 1 | 0 | 0 | 0 | |||||
| Sub-Study Assignments (open studies only) | |||||||||||
| S1800E | 315 | 315 | 124 | 59 | 25 | 5 | |||||
| S1900G | 34 | 6 | 2 | 1 | 0 | 0 | |||||
| S1900J | 17 | 8 | 4 | 3 | 2 | 0 | |||||
| S1900K | 36 | 28 | 14 | 10 | 2 | 0 | |||||
| Sub-Study Registrations | |||||||||||
| LUNGMAP Sub-Study Registrations | 594 | 99 | 63 | 38 | 12 | 3 | |||||
| Initial sub-study registrations | 582 | 99 | 63 | 38 | 12 | 3 | |||||
| Subsequent sub-study registrations | 12 | 0 | 0 | 0 | 0 | 0 | |||||
| Patients Registered to a Sub-Study (open studies only) | |||||||||||
| S1800E: Non-Match: Docetaxel + Ramu +/- Cemiplimab | 378 | 68 | 68 | 47 | 28 | 9 | 2 | 05/22/2025 | 354 | 113 | |
| Docetaxel plus Ramucirumab | Y | 36 | 36 | 24 | 15 | 6 | 2 | ||||
| Cemiplimab plus Docetaxel and Ramucirumab | Y | 32 | 32 | 23 | 13 | 3 | 0 | ||||
| S1900G: EGFR-Mut, MET-Amp: Capmat + Osimert +/- Ramu | 66 | 24 | 7 | 3 | 1 | 0 | 0 | 05/05/2023 | 342 | 109 | |
| Capmatinib + Osimertinib + Ramucirumab | Y | 14 | 6 | 3 | 1 | 0 | 0 | ||||
| Capmatinib + Osimertinib | Y | 10 | 1 | 0 | 0 | 0 | 0 | ||||
| S1900J: MET Amplification: Amivantamab Hyaluronidase | 88 | 4 | 3 | 2 | 1 | 1 | 1 | 11/19/2024 | 242 | 80 | |
| Amivantamab Hyaluronidase | Y | 4 | 3 | 2 | 1 | 1 | 1 | ||||
| S1900K: MET Exon 14: Tepotinib +/- Ramucirumab | 56 | 24 | 21 | 11 | 8 | 2 | 0 | 08/08/2024 | 270 | 89 | |
| Tepotinib + Ramucirumab | Y | 16 | 14 | 8 | 6 | 2 | 0 | ||||
| Tepotinib | Y | 8 | 7 | 3 | 2 | 0 | 0 | ||||