31-DEC-2025 6:10

LUNG ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support
STUDY R
E
G
O
P
E
N
ARM ACCR.
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
SWOG S1933-NSCLC, Stg II-III, RT + Atezo 1 Y 1 Hypofractionated Radiotherapy 47 47 6 2 0 0 0 01/13/2021 116 36
            47 6 2 0 0 0      
 
    2 Y 2 Atezolizumab   38 7 4 2 0 0 01/13/2021    
            38 7 4 2 0 0      
 
  S2409-ESCLC, Durvalumab +/- Biomarker Directed Tx 1 Y 0 Screening & Cohort Assignment 900 7 7 7 7 3 2 11/06/2025 152 43
            7 7 7 7 3 2      
 
  S2414-NSCLC, Stg II-IIIB, Durva vs Surveillance 1 Y 1 Durvalumab 306 3 3 1 1 0 0 04/01/2025 276 77
        2 Surveillance   2 2 2 1 0 0      
            5 5 3 2 0 0      
 
Yes A081801-ALCHEMIST4, ALK and EGFR negative, Chemo-IO 1 E Total Registrations   101 14 9 3 1 0 10/20/2020 417 164
            101 14 9 3 1 0      
 
  EA5162-NSCLC,StgIV/IIB,EGFR exon20 insertion,AZD9291 1 E Total Registrations   4 3 0 0 0 0 08/23/2023 98 35
            4 3 0 0 0 0      
 
  EA5182-NSCLC, Met EGFR mut, AZD9291+Beva vs AZD9291 1 E Total Registrations   25 4 1 0 0 0 04/28/2021 220 82
            25 4 1 0 0 0      
 
  EA5221-Lung, Advanced NSCLC, ChemoImmuno/Immuno 1 E Total Registrations   5 4 2 1 0 0 08/07/2024 210 80
            5 4 2 1 0 0      
 
    2 E Total Registrations   4 3 2 1 0 0 08/07/2024    
            4 3 2 1 0 0      
 
  NRGLU008-Lung NSCL, StgII-III, StereoBodyRad/MedChemo 1 E Total Registrations   5 3 2 0 0 0 01/26/2024 316 127
            5 3 2 0 0 0      
 
No S2402-NSCLC, All Stg, Periop Vs Adj Tx 1 E Total Registrations   6 6 2 2 2 0 04/22/2025 139 61
            6 6 2 2 2 0      
 
  A082002-Lung, Adv, Systemic Tx +/- SBRT 1 E Total Registrations   4 0 0 0 0 0 10/12/2022 258 74
            4 0 0 0 0 0      
 
  EA5231-Lung, Stg II-IIIB, CheckBlock 0 E Total Registrations   1 1 1 1 1 0 12/15/2025 4 1
            1 1 1 1 1 0      
 
    1 E Total Registrations   1 1 1 1 1 0 12/15/2025    
            1 1 1 1 1 0      
 

31-DEC-2025 6:10

LUNG Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs
# of
CURR
IRBs
S2409 ESCLC, Durvalumab +/- Biomarker Directed Tx 2 Randomization 08-Sep-25 152 43