| SWOG/ Support |
STUDY | R E G |
O P E N |
ARM | ACCR. GOAL |
TOTAL REGS. |
REGS. LAST 12 Month |
REGS. LAST 6 Month |
REGS. LAST 3 Month |
REGS. LAST 30 DAYS |
REGS. LAST 7 DAYS |
DATE OF FIRST REG. |
# of ACT. INSTs |
# of CURR IRBs |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SWOG | S1925-CLL/SLL, Newly Dx HR, Early vs Delayed V+O | 1 | Y | 1 Delayed V-O | 247 | 71 | 17 | 8 | 3 | 1 | 0 | 03/02/2021 | 269 | 88 |
| 2 Early V-O | 138 | 35 | 22 | 8 | 2 | 0 | ||||||||
| 209 | 52 | 30 | 11 | 3 | 0 | |||||||||
| S2504-Richter Trans., Untreated, R-CHOP +/- Pirto | 1 | Y | 1 Pirtobrutinib + R-CHOP (Safety Run-in) | 102 | 1 | 1 | 1 | 1 | 0 | 0 | 08/04/2026 | 65 | 21 | |
| 1 | 1 | 1 | 1 | 0 | 0 | |||||||||
| 21CTP.LEUK01-ALL, Ph+, Asciminib, Dasatinib and Prednisone | 1 | Y | 1 Asciminib+Dasatinib+PRED / Blinatumomab+Dasatinib | 55 | 7 | 7 | 7 | 4 | 0 | 0 | 04/13/2026 | |||
| 7 | 7 | 7 | 4 | 0 | 0 | |||||||||
| 2 | Y | 2 Blinatumomab + Dasatinib + MTX + DXM | 2 | 2 | 2 | 2 | 1 | 0 | 04/13/2026 | |||||
| 2 | 2 | 2 | 2 | 1 | 0 | |||||||||
| MM1OA-S03-AML, Newly Dx, Ven+ASTX727 vs Ven+ASTX727+Ena | 1 | Y | 1 ASTX727 + Venetoclax + Enasidenib (Safety Run-in) | 102 | 8 | 2 | 0 | 0 | 0 | 0 | 05/16/2025 | 239 | 64 | |
| 2 ASTX727 + Venetoclax | 11 | 11 | 11 | 5 | 2 | 0 | ||||||||
| 3 ASTX727 + Venetoclax + Enasidenib | 9 | 9 | 9 | 4 | 1 | 0 | ||||||||
| 28 | 22 | 20 | 9 | 3 | 0 | |||||||||
| MM1OA-S04-MyeloMATCH: AML, ASTX727 + Ven (28D v 14D) | 1 | Y | 1 Venetoclax (28D) + ASTX727 | 126 | 1 | 1 | 1 | 1 | 1 | 1 | 09/25/2026 | 77 | 27 | |
| 1 | 1 | 1 | 1 | 1 | 1 | |||||||||
| MM1YA-S01-AML, High Risk, Age <60, 7+3 vs experimental | 1 | Y | 1 Daunorubicin + Cytarabine | 335 | 18 | 8 | 5 | 3 | 1 | 0 | 09/25/2024 | 299 | 108 | |
| 2 Venetoclax + Daunorubicin + Cytarabine | 19 | 11 | 7 | 3 | 2 | 0 | ||||||||
| 3 Venetoclax + Azacitidine | 18 | 10 | 5 | 2 | 2 | 0 | ||||||||
| 4 (Daunorubicin + Cytarabine) Liposome | 18 | 9 | 3 | 3 | 1 | 1 | ||||||||
| 5 (Daunorubicin + Cytarabine) Liposome + Venetoclax | 18 | 10 | 6 | 3 | 1 | 0 | ||||||||
| 91 | 48 | 26 | 14 | 7 | 1 | |||||||||
| MYELOMATCH-MSRP for the NCI myeloMATCH Clinical Trials | 1 | Y | 1 Screening | 1324 | 614 | 315 | 157 | 55 | 9 | 06/18/2024 | 372 | 144 | ||
| 1324 | 614 | 315 | 157 | 55 | 9 | |||||||||
| 2 | Y | 2 Re-screening | 161 | 102 | 47 | 14 | 4 | 3 | 06/18/2024 | |||||
| 161 | 102 | 47 | 14 | 4 | 3 | |||||||||
| 3 | Y | 3 Re-screening | 51 | 40 | 20 | 6 | 1 | 1 | 06/18/2024 | |||||
| 51 | 40 | 20 | 6 | 1 | 1 | |||||||||
| 4 | Y | 4 Re-screening | 10 | 9 | 8 | 4 | 1 | 0 | 06/18/2024 | |||||
| 10 | 9 | 8 | 4 | 1 | 0 | |||||||||
| Yes | EA9213-T-ALL, dara-hyal for chemo refractory MRD | 0 | E | Total Registrations | 9 | 3 | 1 | 0 | 0 | 0 | 02/24/2023 | 114 | 38 | |
| 9 | 3 | 1 | 0 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 4 | 1 | 1 | 0 | 0 | 0 | 02/24/2023 | |||||
| 4 | 1 | 1 | 0 | 0 | 0 | |||||||||
| No | A041501-B-Cell ALL, Frontline Tx +/- Intuzumab Ozo | 0 | E | Total Registrations | 75 | 4 | 2 | 2 | 0 | 0 | 11/09/2018 | 308 | 88 | |
| 75 | 4 | 2 | 2 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 60 | 3 | 2 | 2 | 0 | 0 | 11/09/2018 | |||||
| 60 | 3 | 2 | 2 | 0 | 0 | |||||||||
| 2 | E | Total Registrations | 44 | 0 | 0 | 0 | 0 | 0 | 11/09/2018 | |||||
| 44 | 0 | 0 | 0 | 0 | 0 | |||||||||
| A041703-ALL, Newly Dx, Inotuzumab Ozogamicin + Blinat | 0 | E | Total Registrations | 13 | 2 | 2 | 1 | 0 | 0 | 08/13/2020 | 166 | 46 | ||
| 13 | 2 | 2 | 1 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 7 | 2 | 2 | 1 | 0 | 0 | 08/13/2020 | |||||
| 7 | 2 | 2 | 1 | 0 | 0 | |||||||||
| MM1MDS-A01-MYELOMATCH, Hi-Risk IDH2, Enas vs Cedaz | 1 | P | Total Registrations | 2 | 2 | 2 | 2 | 1 | 0 | 08/12/2026 | 168 | 51 | ||
| 2 | 2 | 2 | 2 | 1 | 0 | |||||||||
| MM1OA-EA02-MyeloMATCH: AML, New Dx, Ven+HMA | 1 | E | Total Registrations | 19 | 10 | 2 | 0 | 0 | 0 | 12/02/2024 | 301 | 103 | ||
| 19 | 10 | 2 | 0 | 0 | 0 | |||||||||
| MM1YA-CTG01-MyeloMATCH: AML, New Dx w/ Int Risk, Ven+Chem | 1 | E | Total Registrations | 14 | 9 | 6 | 2 | 0 | 0 | 10/14/2024 | 280 | 91 | ||
| 14 | 9 | 6 | 2 | 0 | 0 | |||||||||
| Study | Registration/Phase | Open Date | # of ACT. INSTs |
# of CURR IRBs |
|---|---|---|---|---|
| S2507 ALL/ALAL, KMT2A-trans, Blina +/- Revumenib | 1 Registration | 22-Sep-26 | ||
| 21CTP.LEUK01 ALL, Ph+, Asciminib, Dasatinib and Prednisone | 3 Maintenance | 11-Dec-25 |