| SWOG/ Support |
STUDY | R E G |
O P E N |
ARM | ACCR. GOAL |
TOTAL REGS. |
REGS. LAST 12 Month |
REGS. LAST 6 Month |
REGS. LAST 3 Month |
REGS. LAST 30 DAYS |
REGS. LAST 7 DAYS |
DATE OF FIRST REG. |
# of ACT. INSTs |
# of CURR IRBs |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SWOG | S1905-T-ALL/T-LBL, Rel/Ref, OBI-3424 | 1 | T | 1 OBI-3424 8mg | 67 | 5 | 0 | 0 | 0 | 0 | 0 | 02/08/2021 | 84 | 42 |
| 2 OBI-3424 10mg | 5 | 0 | 0 | 0 | 0 | 0 | ||||||||
| 3 OBI-3424 12mg | 14 | 6 | 5 | 3 | 0 | 0 | ||||||||
| 24 | 6 | 5 | 3 | 0 | 0 | |||||||||
| S1925-CLL/SLL, Newly Dx HR, Early vs Delayed V+O | 1 | Y | 1 Delayed V-O | 247 | 58 | 17 | 8 | 5 | 2 | 1 | 03/02/2021 | 273 | 93 | |
| 2 Early V-O | 107 | 29 | 11 | 6 | 3 | 1 | ||||||||
| 165 | 46 | 19 | 11 | 5 | 2 | |||||||||
| MM1OA-S03-AML, Newly Dx, Ven+ASTX727 vs Ven+ASTX727+Ena | 1 | T | 1 ASTX727 + Venetoclax + Enasidenib (Safety Run-in) | 102 | 8 | 8 | 7 | 5 | 0 | 0 | 05/16/2025 | 197 | 56 | |
| 8 | 8 | 7 | 5 | 0 | 0 | |||||||||
| MM1YA-S01-AML, High Risk, Age <60, 7+3 vs experimental | 1 | Y | 1 Daunorubicin + Cytarabine | 335 | 10 | 10 | 7 | 4 | 0 | 0 | 09/25/2024 | 286 | 99 | |
| 2 Venetoclax + Daunorubicin + Cytarabine | 10 | 10 | 7 | 4 | 2 | 1 | ||||||||
| 3 Venetoclax + Azacitidine | 11 | 10 | 7 | 5 | 3 | 0 | ||||||||
| 4 (Daunorubicin + Cytarabine) Liposome | 11 | 10 | 7 | 5 | 1 | 0 | ||||||||
| 5 (Daunorubicin + Cytarabine) Liposome + Venetoclax | 8 | 7 | 5 | 2 | 0 | 0 | ||||||||
| 50 | 47 | 33 | 20 | 6 | 1 | |||||||||
| MYELOMATCH-MSRP for the NCI myeloMATCH Clinical Trials | 1 | Y | 1 Screening | 796 | 682 | 328 | 165 | 54 | 13 | 06/18/2024 | 347 | 135 | ||
| 796 | 682 | 328 | 165 | 54 | 13 | |||||||||
| 2 | Y | 2 Re-screening | 69 | 66 | 28 | 16 | 7 | 0 | 06/18/2024 | |||||
| 69 | 66 | 28 | 16 | 7 | 0 | |||||||||
| 3 | Y | 3 Re-screening | 20 | 20 | 14 | 11 | 6 | 0 | 06/18/2024 | |||||
| 20 | 20 | 14 | 11 | 6 | 0 | |||||||||
| 4 | Y | 4 Re-screening | 1 | 1 | 0 | 0 | 0 | 0 | 06/18/2024 | |||||
| 1 | 1 | 0 | 0 | 0 | 0 | |||||||||
| Yes | EA9213-T-ALL, dara-hyal for chemo refractory MRD | 0 | E | Total Registrations | 6 | 1 | 0 | 0 | 0 | 0 | 02/24/2023 | 104 | 35 | |
| 6 | 1 | 0 | 0 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 3 | 0 | 0 | 0 | 0 | 0 | 02/24/2023 | |||||
| 3 | 0 | 0 | 0 | 0 | 0 | |||||||||
| No | A041501-B-Cell ALL, Frontline Tx +/- Intuzumab Ozo | 0 | E | Total Registrations | 71 | 0 | 0 | 0 | 0 | 0 | 11/09/2018 | 275 | 86 | |
| 71 | 0 | 0 | 0 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 57 | 0 | 0 | 0 | 0 | 0 | 11/09/2018 | |||||
| 57 | 0 | 0 | 0 | 0 | 0 | |||||||||
| 2 | E | Total Registrations | 44 | 0 | 0 | 0 | 0 | 0 | 11/09/2018 | |||||
| 44 | 0 | 0 | 0 | 0 | 0 | |||||||||
| A041703-ALL, Newly Dx, Inotuzumab Ozogamicin + Blinat | 0 | E | Total Registrations | 11 | 0 | 0 | 0 | 0 | 0 | 08/13/2020 | 150 | 49 | ||
| 11 | 0 | 0 | 0 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 5 | 0 | 0 | 0 | 0 | 0 | 08/13/2020 | |||||
| 5 | 0 | 0 | 0 | 0 | 0 | |||||||||
| EA9181-ALL, BCR-ABL+, Steroids+TKI+CT/Blinatumomab | 0 | E | Total Registrations | 63 | 18 | 10 | 5 | 3 | 0 | 02/19/2021 | 180 | 55 | ||
| 63 | 18 | 10 | 5 | 3 | 0 | |||||||||
| 1 | E | Total Registrations | 51 | 14 | 7 | 3 | 2 | 0 | 02/19/2021 | |||||
| 51 | 14 | 7 | 3 | 2 | 0 | |||||||||
| 2 | E | Total Registrations | 45 | 12 | 8 | 3 | 2 | 1 | 02/19/2021 | |||||
| 45 | 12 | 8 | 3 | 2 | 1 | |||||||||
| MM1OA-EA02-MyeloMATCH: AML, New Dx, Ven+HMA | 1 | E | Total Registrations | 9 | 9 | 5 | 3 | 0 | 0 | 12/02/2024 | ||||
| 9 | 9 | 5 | 3 | 0 | 0 | |||||||||
| MM1YA-CTG01-MyeloMATCH: AML, New/Young/Int, Ven+Chemo | 1 | E | Total Registrations | 5 | 3 | 3 | 1 | 0 | 0 | 10/14/2024 | ||||
| 5 | 3 | 3 | 1 | 0 | 0 | |||||||||
| Study | Registration/Phase | Open Date | # of ACT. INSTs |
# of CURR IRBs |
|---|---|---|---|---|
| 21CTP.LEUK01 ALL, Ph+, Asciminib, Dasatinib and Prednisone | 1 Initial Registration | 15-May-25 | ||
| 2 Post-Remission | 15-May-25 | |||
| 3 Maintenance | 15-May-25 | |||
| EA9181 ALL, BCR-ABL+, Steroids+TKI+CT/Blinatumomab | 3 Randomization | 14-Oct-20 | 180 | 55 |