08-SEP-2026 6:10

LEUK ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support
STUDY R
E
G
O
P
E
N
ARM ACCR.
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
SWOG S1925-CLL/SLL, Newly Dx HR, Early vs Delayed V+O 1 Y 1 Delayed V-O 247 71 18 9 5 1 0 03/02/2021 269 89
        2 Early V-O   137 36 23 13 1 0      
            208 54 32 18 2 0      
 
  S2504-Richter Trans., Untreated, R-CHOP +/- Pirto 1 Y 1 Pirtobrutinib + R-CHOP (Safety Run-in) 102 1 1 1 1 0 0 08/04/2026 47 15
            1 1 1 1 0 0      
 
  21CTP.LEUK01-ALL, Ph+, Asciminib, Dasatinib and Prednisone 1 Y 1 Asciminib+Dasatinib+PRED / Blinatumomab+Dasatinib 55 7 7 7 6 1 0 04/13/2026    
            7 7 7 6 1 0      
 
    2 Y 2 Blinatumomab + Dasatinib + MTX + DXM   1 1 1 1 0 0 04/13/2026    
            1 1 1 1 0 0      
 
  MM1OA-S03-AML, Newly Dx, Ven+ASTX727 vs Ven+ASTX727+Ena 1 Y 1 ASTX727 + Venetoclax + Enasidenib (Safety Run-in) 102 8 5 0 0 0 0 05/16/2025 238 64
        2 ASTX727 + Venetoclax   9 9 9 5 2 0      
        3 ASTX727 + Venetoclax + Enasidenib   8 8 8 5 2 0      
            25 22 17 10 4 0      
 
  MM1YA-S01-AML, High Risk, Age <60, 7+3 vs experimental 1 Y 1 Daunorubicin + Cytarabine 335 17 9 4 2 1 0 09/25/2024 298 108
        2 Venetoclax + Daunorubicin + Cytarabine   17 10 7 1 0 0      
        3 Venetoclax + Azacitidine   16 9 3 1 0 0      
        4 (Daunorubicin + Cytarabine) Liposome   17 10 4 2 1 0      
        5 (Daunorubicin + Cytarabine) Liposome + Venetoclax   17 11 6 2 1 0      
            84 49 24 8 3 0      
 
  MYELOMATCH-MSRP for the NCI myeloMATCH Clinical Trials 1 Y 1 Screening   1284 616 308 148 49 7 06/18/2024 367 141
            1284 616 308 148 49 7      
 
    2 Y 2 Re-screening   157 103 54 17 4 0 06/18/2024    
            157 103 54 17 4 0      
 
    3 Y 3 Re-screening   50 39 22 7 1 0 06/18/2024    
            50 39 22 7 1 0      
 
    4 Y 4 Re-screening   9 8 7 3 1 0 06/18/2024    
            9 8 7 3 1 0      
 
Yes EA9213-T-ALL, dara-hyal for chemo refractory MRD 0 E Total Registrations   9 3 2 0 0 0 02/24/2023 114 38
            9 3 2 0 0 0      
 
    1 E Total Registrations   4 1 1 0 0 0 02/24/2023    
            4 1 1 0 0 0      
 
No A041501-B-Cell ALL, Frontline Tx +/- Intuzumab Ozo 0 E Total Registrations   75 4 2 2 0 0 11/09/2018 307 88
            75 4 2 2 0 0      
 
    1 E Total Registrations   60 3 2 2 0 0 11/09/2018    
            60 3 2 2 0 0      
 
    2 E Total Registrations   44 0 0 0 0 0 11/09/2018    
            44 0 0 0 0 0      
 
  A041703-ALL, Newly Dx, Inotuzumab Ozogamicin + Blinat 0 E Total Registrations   13 2 2 1 1 0 08/13/2020 165 46
            13 2 2 1 1 0      
 
    1 E Total Registrations   7 2 2 1 1 0 08/13/2020    
            7 2 2 1 1 0      
 
  MM1MDS-A01-MYELOMATCH, Hi-Risk IDH2, Enas vs Cedaz 1 P Total Registrations   1 1 1 1 1 0 08/12/2026 167 51
            1 1 1 1 1 0      
 
  MM1OA-EA02-MyeloMATCH: AML, New Dx, Ven+HMA 1 E Total Registrations   19 10 3 1 0 0 12/02/2024 300 103
            19 10 3 1 0 0      
 
  MM1YA-CTG01-MyeloMATCH: AML, New Dx w/ Int Risk, Ven+Chem 1 E Total Registrations   14 10 6 4 1 0 10/14/2024 279 90
            14 10 6 4 1 0      
 

08-SEP-2026 6:10

LEUK Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs
# of
CURR
IRBs
21CTP.LEUK01 ALL, Ph+, Asciminib, Dasatinib and Prednisone 3 Maintenance 11-Dec-25    
MM1OA-S04 MyeloMATCH: AML, ASTX727 + Ven (28D v 14D) 1 Randomization 22-Jul-26 67 21