| SWOG/ Support |
STUDY | R E G |
O P E N |
ARM | ACCR. GOAL |
TOTAL REGS. |
REGS. LAST 12 Month |
REGS. LAST 6 Month |
REGS. LAST 3 Month |
REGS. LAST 30 DAYS |
REGS. LAST 7 DAYS |
DATE OF FIRST REG. |
# of ACT. INSTs |
# of CURR IRBs |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SWOG | S1925-CLL/SLL, Newly Dx HR, Early vs Delayed V+O | 1 | Y | 1 Delayed V-O | 247 | 74 | 17 | 9 | 4 | 2 | 0 | 03/02/2021 | 271 | 89 |
| 2 Early V-O | 140 | 34 | 17 | 4 | 1 | 0 | ||||||||
| 214 | 51 | 26 | 8 | 3 | 0 | |||||||||
| S2504-Richter Trans., Untreated, R-CHOP +/- Pirto | 1 | Y | 1 Pirtobrutinib + R-CHOP (Safety Run-in) | 102 | 3 | 3 | 3 | 2 | 2 | 1 | 08/04/2026 | 117 | 29 | |
| 3 | 3 | 3 | 2 | 2 | 1 | |||||||||
| 21CTP.LEUK01-ALL, Ph+, Asciminib, Dasatinib and Prednisone | 1 | Y | 1 Asciminib+Dasatinib+PRED / Blinatumomab+Dasatinib | 55 | 9 | 9 | 8 | 3 | 2 | 0 | 04/13/2026 | |||
| 9 | 9 | 8 | 3 | 2 | 0 | |||||||||
| 2 | Y | 2 Blinatumomab + Dasatinib + MTX + DXM | 6 | 6 | 6 | 5 | 2 | 1 | 04/13/2026 | |||||
| 6 | 6 | 6 | 5 | 2 | 1 | |||||||||
| MM1OA-S03-AML, Newly Dx, Ven+ASTX727 vs Ven+ASTX727+Ena | 1 | Y | 1 ASTX727 + Venetoclax + Enasidenib (Safety Run-in) | 102 | 8 | 0 | 0 | 0 | 0 | 0 | 05/16/2025 | 199 | 56 | |
| 2 ASTX727 + Venetoclax | 13 | 13 | 12 | 6 | 2 | 0 | ||||||||
| 3 ASTX727 + Venetoclax + Enasidenib | 13 | 13 | 11 | 6 | 3 | 1 | ||||||||
| 34 | 26 | 23 | 12 | 5 | 1 | |||||||||
| MM1OA-S04-MyeloMATCH: AML, ASTX727 + Ven (28D v 14D) | 1 | Y | 1 Venetoclax (28D) + ASTX727 | 126 | 1 | 1 | 1 | 1 | 0 | 0 | 09/25/2026 | 113 | 38 | |
| 1 | 1 | 1 | 1 | 0 | 0 | |||||||||
| MM1YA-S01-AML, High Risk, Age <60, 7+3 vs experimental | 1 | Y | 1 Daunorubicin + Cytarabine | 335 | 20 | 10 | 6 | 4 | 2 | 0 | 09/25/2024 | 300 | 108 | |
| 2 Venetoclax + Daunorubicin + Cytarabine | 20 | 11 | 6 | 3 | 1 | 0 | ||||||||
| 3 Venetoclax + Azacitidine | 19 | 8 | 4 | 3 | 1 | 0 | ||||||||
| 4 (Daunorubicin + Cytarabine) Liposome | 19 | 8 | 4 | 2 | 0 | 0 | ||||||||
| 5 Venetoclax + (Daunorubicin + Cytarabine) Liposome | 20 | 12 | 7 | 4 | 2 | 0 | ||||||||
| 98 | 49 | 27 | 16 | 6 | 0 | |||||||||
| MYELOMATCH-MSRP for the NCI myeloMATCH Clinical Trials | 1 | Y | 1 Screening | 1397 | 614 | 310 | 161 | 54 | 13 | 06/18/2024 | 373 | 145 | ||
| 1397 | 614 | 310 | 161 | 54 | 13 | |||||||||
| 2 | Y | 2 Re-screening | 173 | 104 | 37 | 20 | 8 | 4 | 06/18/2024 | |||||
| 173 | 104 | 37 | 20 | 8 | 4 | |||||||||
| 3 | Y | 3 Re-screening | 59 | 40 | 18 | 10 | 4 | 0 | 06/18/2024 | |||||
| 59 | 40 | 18 | 10 | 4 | 0 | |||||||||
| 4 | Y | 4 Re-screening | 10 | 9 | 7 | 1 | 0 | 0 | 06/18/2024 | |||||
| 10 | 9 | 7 | 1 | 0 | 0 | |||||||||
| Yes | EA9213-T-ALL, dara-hyal for chemo refractory MRD | 0 | E | Total Registrations | 9 | 3 | 0 | 0 | 0 | 0 | 02/24/2023 | 115 | 38 | |
| 9 | 3 | 0 | 0 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 4 | 1 | 0 | 0 | 0 | 0 | 02/24/2023 | |||||
| 4 | 1 | 0 | 0 | 0 | 0 | |||||||||
| No | A041501-B-Cell ALL, Frontline Tx +/- Intuzumab Ozo | 0 | E | Total Registrations | 76 | 5 | 3 | 1 | 0 | 0 | 11/09/2018 | 309 | 88 | |
| 76 | 5 | 3 | 1 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 60 | 3 | 2 | 0 | 0 | 0 | 11/09/2018 | |||||
| 60 | 3 | 2 | 0 | 0 | 0 | |||||||||
| 2 | E | Total Registrations | 44 | 0 | 0 | 0 | 0 | 0 | 11/09/2018 | |||||
| 44 | 0 | 0 | 0 | 0 | 0 | |||||||||
| A041703-ALL, Newly Dx, Inotuzumab Ozogamicin + Blinat | 0 | E | Total Registrations | 13 | 2 | 1 | 1 | 0 | 0 | 08/13/2020 | 167 | 47 | ||
| 13 | 2 | 1 | 1 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 7 | 2 | 1 | 1 | 0 | 0 | 08/13/2020 | |||||
| 7 | 2 | 1 | 1 | 0 | 0 | |||||||||
| MM1MDS-A01-MYELOMATCH, Hi-Risk IDH2, Enas vs Cedaz | 1 | P | Total Registrations | 2 | 2 | 2 | 2 | 0 | 0 | 08/12/2026 | 169 | 51 | ||
| 2 | 2 | 2 | 2 | 0 | 0 | |||||||||
| MM1OA-EA02-MyeloMATCH: AML, New Dx, Ven+HMA | 1 | E | Total Registrations | 22 | 13 | 4 | 3 | 3 | 1 | 12/02/2024 | 302 | 105 | ||
| 22 | 13 | 4 | 3 | 3 | 1 | |||||||||
| MM1YA-CTG01-MyeloMATCH: AML, New Dx w/ Int Risk, Ven+Chem | 1 | E | Total Registrations | 15 | 10 | 6 | 2 | 1 | 0 | 10/14/2024 | 281 | 91 | ||
| 15 | 10 | 6 | 2 | 1 | 0 | |||||||||
| Study | Registration/Phase | Open Date | # of ACT. INSTs |
# of CURR IRBs |
|---|---|---|---|---|
| S2507 ALL/ALAL, KMT2A-trans, Blina +/- Revumenib | 1 Registration | 22-Sep-26 | 68 | 11 |
| 21CTP.LEUK01 ALL, Ph+, Asciminib, Dasatinib and Prednisone | 3 Maintenance | 11-Dec-25 |