Table 1
| SWOG/ Support |
STUDY | R E G |
O P E N |
ARM | ACCR. GOAL |
TOTAL REGS. |
REGS. LAST 12 Month |
REGS. LAST 6 Month |
REGS. LAST 3 Month |
REGS. LAST 30 DAYS |
REGS. LAST 7 DAYS |
DATE OF FIRST REG. |
# of ACT. INSTs |
# of CURR IRBs |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SWOG | S1500-pRCC,Adv, Sunitinib vs MET inhib | 1 | Y | 1 Sunitinib | 148 | 35 | 14 | 5 | 3 | 1 | 0 | 07/25/2016 | 215 | 87 |
| 2 Cabozantinib | 34 | 12 | 6 | 4 | 1 | 0 | ||||||||
| 3 Crizotinib | 28 | 6 | 0 | 0 | 0 | 0 | ||||||||
| 4 Savolitinib | 30 | 8 | 0 | 0 | 0 | 0 | ||||||||
| 127 | 40 | 11 | 7 | 2 | 0 | |||||||||
| S1602-Blad, HG NMIBC, TICE/Tokyo/Prime+Tokyo BCG | 1 | Y | 1 TICE BCG | 969 | 136 | 100 | 69 | 49 | 18 | 3 | 02/24/2017 | 177 | 77 | |
| 2 Tokyo-172 BCG | 135 | 98 | 68 | 48 | 16 | 4 | ||||||||
| 3 Prime + Tokyo-172 BCG | 132 | 94 | 66 | 46 | 15 | 2 | ||||||||
| 403 | 292 | 203 | 143 | 49 | 9 | |||||||||
| S1605-Blad, BCG-Unresponsive NMIBC, Atezolizumab | 1 | Y | 1 Atezolizumab | 162 | 168 | 117 | 62 | 38 | 11 | 1 | 03/13/2017 | 208 | 93 | |
| 168 | 117 | 62 | 38 | 11 | 1 | |||||||||
| S1802-Pros, Stg IV, SST +/- Surg/RT to Primary Tum | 1 | Y | 0 Induction SST | 1273 | 68 | 68 | 46 | 27 | 6 | 1 | 09/24/2018 | 245 | 101 | |
| 68 | 68 | 46 | 27 | 6 | 1 | |||||||||
| 2 | Y | 1 Standard Systemic Therapy Only | 1273 | 16 | 16 | 12 | 9 | 1 | 0 | 09/24/2018 | ||||
| 2 SST + Surgery/RT | 18 | 18 | 14 | 11 | 4 | 0 | ||||||||
| 34 | 34 | 26 | 20 | 5 | 0 | |||||||||
| S1806-Blad, MIBC, ChemoRT +/- Atezolizumab | 1 | Y | 0 Initial Registration | 475 | 1 | 1 | 1 | 1 | 1 | 0 | 06/03/2019 | 130 | 60 | |
| 1 | 1 | 1 | 1 | 1 | 0 | |||||||||
| 2 | Y | 1 Chemo + RT | 475 | 1 | 1 | 1 | 1 | 1 | 0 | 06/03/2019 | ||||
| 1 | 1 | 1 | 1 | 1 | 0 | |||||||||
| Yes | A031102-GCT, Recur, Std Chemo(TIP) vs HD Chemo(TI-CE) | 1 | E | Total Registrations | 5 | 2 | 1 | 1 | 0 | 0 | 11/23/2016 | 61 | 37 | |
| 5 | 2 | 1 | 1 | 0 | 0 | |||||||||
| EA8143-RCC, HR, Surg +/- Nivolumab (PROSPER) | 0 | E | Total Registrations | 52 | 36 | 26 | 13 | 4 | 2 | 09/29/2017 | 275 | 135 | ||
| 52 | 36 | 26 | 13 | 4 | 2 | |||||||||
| 1 | E | Total Registrations | 43 | 31 | 23 | 14 | 2 | 0 | 09/29/2017 | |||||
| 43 | 31 | 23 | 14 | 2 | 0 | |||||||||
| EA8171-PROS, newly diagnosed, mpMRI for pre-op stagi | 1 | E | Total Registrations | 6 | 6 | 6 | 4 | 1 | 1 | 02/11/2019 | 81 | 32 | ||
| 6 | 6 | 6 | 4 | 1 | 1 | |||||||||
| NRGGU002-Pros, RT + ADT After RP +/- Adj Docetaxel | 1 | E | Total Registrations | 3 | 2 | 1 | 0 | 0 | 0 | 08/24/2017 | 228 | 110 | ||
| 3 | 2 | 1 | 0 | 0 | 0 | |||||||||
| 2 | E | Total Registrations | 3 | 2 | 1 | 1 | 0 | 0 | 08/24/2017 | |||||
| 3 | 2 | 1 | 1 | 0 | 0 | |||||||||
| NRGGU005-PROS, intmd risk, IGRT& SBRT vs IGRT& HF-IMRT | 1 | E | Total Registrations | 1 | 1 | 1 | 1 | 0 | 0 | 03/19/2019 | 53 | 26 | ||
| 1 | 1 | 1 | 1 | 0 | 0 | |||||||||
| NRGGU006-PROS, post-RP PSA, SRT +/- ADT w/Apalutamide | 1 | E | Total Registrations | 2 | 2 | 2 | 2 | 0 | 0 | 03/22/2019 | 50 | 18 | ||
| 2 | 2 | 2 | 2 | 0 | 0 | |||||||||
| 2 | E | Total Registrations | 2 | 2 | 2 | 2 | 0 | 0 | 03/22/2019 | |||||
| 2 | 2 | 2 | 2 | 0 | 0 | |||||||||
| No | A031501-Bladder, MIBC/Loc Adv, Adjv Pembro vs Obs | 0 | E | Total Registrations | 38 | 35 | 20 | 7 | 0 | 0 | 05/03/2018 | 244 | 129 | |
| 38 | 35 | 20 | 7 | 0 | 0 | |||||||||
| 1 | E | Total Registrations | 37 | 36 | 25 | 10 | 2 | 0 | 05/03/2018 | |||||
| 37 | 36 | 25 | 10 | 2 | 0 | |||||||||
| A031701-Bladder, ddGC for MIBC with DDR Tumor Alt | 1 | E | Total Registrations | 1 | 1 | 0 | 0 | 0 | 0 | 12/17/2018 | 97 | 43 | ||
| 1 | 1 | 0 | 0 | 0 | 0 | |||||||||
| 2 | E | Total Registrations | 1 | 1 | 1 | 1 | 0 | 0 | 12/17/2018 | |||||
| 1 | 1 | 1 | 1 | 0 | 0 | |||||||||
| EA8134-Penile, Local Adv, ILND +/- Chemo or ChemoRT | 1 | E | Total Registrations | 1 | 1 | 1 | 1 | 0 | 0 | 04/25/2019 | ||||
| 1 | 1 | 1 | 1 | 0 | 0 | |||||||||
| EA8153-Pros, ADT + Abira +/- Cabazitaxel (CHAARTED2) | 1 | E | Total Registrations | 7 | 7 | 4 | 3 | 1 | 0 | 08/08/2018 | 232 | 94 | ||
| 7 | 7 | 4 | 3 | 1 | 0 | |||||||||
| R0924-Pros, NADT+WPRT vs. NADT+P&SV RT | 1 | E | Total Registrations | 93 | 14 | 3 | 1 | 0 | 0 | 11/25/2013 | 260 | 114 | ||
| 93 | 14 | 3 | 1 | 0 | 0 | |||||||||