03 OCT 2008 05:51                 GU ACCRUAL REPORT - OPEN and recently closed STUDIES                                  
                                                                                                                        
                                                                 REGS.    REGS.    REGS.   REGS.  REGS.   # of    # of  
                                                ACCR.  TOTAL      LAST     LAST     LAST    LAST   LAST ACTIVE CURRENT  
STUDY    REG. ARM                                GOAL  REGS. 12 Months 6 Months 3 Months 30 DAYS 7 DAYS  INSTs    IRBs  
-------- ---- -------------------------------- ------ ------ --------- -------- -------- ------- ------ ------ -------  
S9346    1    1 Combined Androgen Deprivation    3450   3040       255      127       50       0      0    197      86  
                                                      ------ --------- -------- -------- ------- ------                 
                                                        3040       255      127       50       0      0                 
                                                                                                                        
         2    2 Intermittent hormonal therapy    1725    846        73       41       22       8      3    197      86  
              3 Continuous hormonal therapy              823        56       28       15       5      1                 
                                                      ------ --------- -------- -------- ------- ------                 
                                                        1669       129       69       37      13      4                 
                                                                                                                        
                                                                                                                        
S0337    1    1 Blinded Drug                      340      9         9        7        4       1      0    101      22  
              2 Blinded Drug                               8         8        6        4       1      0                 
                                                      ------ --------- -------- -------- ------- ------                 
                                                          17        17       13        8       2      0                 
                                                                                                                        
                                                                                                                        
S0353    1    1 Intravesical Gemcitabine           45     20        13        7        5       2      1    125      38  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          20        13        7        5       2      1                 
                                                                                                                        
                                                                                                                        
S0421    1    1 Docetaxel + Blinded drug          930    142       120       83       49      20      3    262     112  
              2 Docetaxel + Blinded drug                 146       121       87       50      19      4                 
                                                      ------ --------- -------- -------- ------- ------                 
                                                         288       241      170       99      39      7                 
                                                                                                                        
         2    3 Continued Blinded drug            930     28        27       19       12       5      1    262     112  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          28        27       19       12       5      1                 
                                                                                                                        
                                                                                                                        
C90202   1    Total Registrations                         33        12        2        1       1      0             64  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          33        12        2        1       1      0                 
                                                                                                                        
                                                                                                                        
C90203   1    Total Registrations                         16        16       13        7       2      0             57  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          16        16       13        7       2      0                 
                                                                                                                        
                                                                                                                        
E2804    1    Total Registrations                          1         1        1        1       0      0             55  
                                                      ------ --------- -------- -------- ------- ------                 
                                                           1         1        1        1       0      0                 
                                                                                                                        
                                                                                                                        
E2805    1    Total Registrations                        323       152       80       47      16      3            201  
                                                      ------ --------- -------- -------- ------- ------                 
                                                         323       152       80       47      16      3                 
                                                                                                                        
                                                                                                                        
E3805    1    Total Registrations                          2         2        1        0       0      0             27  
                                                      ------ --------- -------- -------- ------- ------                 
                                                           2         2        1        0       0      0                 
                                                                                                                        
                                                                                                                        
MDA3410  1    Total Registrations                         20         0        0        0       0      0                 
                                                      ------ --------- -------- -------- ------- ------                 
                                                          20         0        0        0       0      0                 
                                                                                                                        
                                                                                                                        
PR11     1    1 Radical Intervention                       2         2        1        0       0      0      8      10  
              2 Active Surveillance                        1         1        1        1       0      0                 
                                                      ------ --------- -------- -------- ------- ------                 
                                                           3         3        2        1       0      0                 
                                                                                                                        
                                                                                                                        
R0415    1    Total Registrations                          1         1        1        0       0      0             58  
                                                      ------ --------- -------- -------- ------- ------                 
                                                           1         1        1        0       0      0                 
                                                                                                                        
                                                                                                                        
R0521    1    Total Registrations                         10         9        5        3       1      0            112  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          10         9        5        3       1      0                 
                                                                                                                        
                                                                                                                        
R0524    1    Total Registrations                          3         3        1        0       0      0             33  
                                                      ------ --------- -------- -------- ------- ------                 
                                                           3         3        1        0       0      0                 
                                                                                                                        
                                                                                                                        




















                                                            

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03 OCT 2008 05:51                         GU Open Studies with No Registrations                                         
                                                                                                                        
Study                                    Registration/Phase                  Open Date                                  
---------------------------------------- ----------------------------------- ---------                                  
S0717 RCC, Adv, Bev + MEDI-522           1 Initial Registration              15jun2008                                  
E8802 Renal, Dox + Gemcitabine           1 Endorsed Study                    08may2006                                  

















                                                            

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