03 OCT 2008 05:51                 GI ACCRUAL REPORT - OPEN and recently closed STUDIES                                  
                                                                                                                        
                                                                 REGS.    REGS.    REGS.   REGS.  REGS.   # of    # of  
                                                ACCR.  TOTAL      LAST     LAST     LAST    LAST   LAST ACTIVE CURRENT  
STUDY    REG. ARM                                GOAL  REGS. 12 Months 6 Months 3 Months 30 DAYS 7 DAYS  INSTs    IRBs  
-------- ---- -------------------------------- ------ ------ --------- -------- -------- ------- ------ ------ -------  
S0502    1    1 Imatinib + Bevacizumab            572      1         1        1        1       1      0    113      38  
              2 Imatinib                                   1         1        1        1       0      0                 
                                                      ------ --------- -------- -------- ------- ------                 
                                                           2         2        2        2       1      0                 
                                                                                                                        
         2    3 PET sub-study                     572      1         1        1        1       1      0    113      38  
                                                      ------ --------- -------- -------- ------- ------                 
                                                           1         1        1        1       1      0                 
                                                                                                                        
                                                                                                                        
S0518    1    1 Octreotide, Bevacizumab           283     26        26       23       17       5      1    140      59  
              2 Octreotide,Interferon Alpha-2b            25        25       22       13       3      0                 
                                                      ------ --------- -------- -------- ------- ------                 
                                                          51        51       45       30       8      1                 
                                                                                                                        
         2    3 Octreotide Scan Submission        283     26        26       24       15       6      1    140      59  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          26        26       24       15       6      1                 
                                                                                                                        
                                                                                                                        
S0600    1    1 Cetuximab                        1260     16        15        4        0       0      0    206      87  
              2 Cetuximab + Lower Bevacizumab             18        17        7        0       0      0                 
              3 Cetuximab + Higher Bevacizumab            17        16        5        0       0      0                 
                                                      ------ --------- -------- -------- ------- ------                 
                                                          51        48       16        0       0      0                 
                                                                                                                        
                                                                                                                        
S0727    1    1 Erlotinib+GEM+6 mg/kg IMC-A12     118      4         4        4        4       2      0      3      10  
                                                      ------ --------- -------- -------- ------- ------                 
                                                           4         4        4        4       2      0                 
                                                                                                                        
                                                                                                                        
C80101   1    Total Registrations                         95        21       10        4       2      0            122  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          95        21       10        4       2      0                 
                                                                                                                        
                                                                                                                        
C80405   1    Total Registrations                2289    422       159       41        0       0      0    318     157  
                                                      ------ --------- -------- -------- ------- ------                 
                                                         422       159       41        0       0      0                 
                                                                                                                        
                                                                                                                        
E5202    1    Total Registrations                        223       104       52       25       9      3            173  
                                                      ------ --------- -------- -------- ------- ------                 
                                                         223       104       52       25       9      3                 
                                                                                                                        
                                                                                                                        
E5204    1    Total Registrations                         65        41       17       12       5      0    247     120  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          65        41       17       12       5      0                 
                                                                                                                        
                                                                                                                        
N0147    1    Total Registrations                        504       183       55        2       2      0            187  
                                                      ------ --------- -------- -------- ------- ------                 
                                                         504       183       55        2       2      0                 
                                                                                                                        
                                                                                                                        
R04      1    Total Registrations                         24        11        6        3       2      0    301     136  
                                                      ------ --------- -------- -------- ------- ------                 
                                                          24        11        6        3       2      0                 
                                                                                                                        
                                                                                                                        






























                                                            

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