19-APR-2024 6:10

GI ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support		 STUDY R
E
G		 O
P
E
N		 ARM ACCR.
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
SWOG S1922-Small Bowel,Ram+Pac vs FOLFIRI, mets/unresect 1 Y 1 Ramucirumab + Paclitaxel 94 18 3 2 2 0 0 06/01/2020 145 53
        2 FOLFIRI   14 2 0 0 0 0      
            32 5 2 2 0 0      
 
  S2001-Rando II, Mets Pancreas , BRCA1/2, Comb Chemo 1 Y 1 Olaparib + Pembrolizumab 88 22 5 2 1 0 0 02/22/2021 192 75
        2 Olaparib   25 10 3 0 0 0      
            47 15 5 1 0 0      
 
  S2104-Panc,Resect High-risk,Postop Adj Chemo vs Obs 1 Y 1 Capecitabine Temozolomide 154 26 17 10 4 3 2 05/05/2022 160 60
        2 Observation   15 8 4 3 2 0      
            41 25 14 7 5 2      
 
  S2107-Colorectal, BRAF mut, Enc + CET +/-Nivo 1 Y 1 Nivolumab + Encorafenib + Cetuximab 84 37 25 15 8 3 0 07/19/2022 160 66
        2 Encorafenib Cetuximab   22 12 5 2 1 0      
            59 37 20 10 4 0      
 
Yes A021806-Pancreas, Perioperative vs Adjuvant Chemo 0 E Total Registrations   35 10 4 1 0 0 10/08/2020 254 116
            35 10 4 1 0 0      
 
    1 E Total Registrations   29 9 5 1 0 0 10/08/2020    
            29 9 5 1 0 0      
 
  A022001-PANC, METS, Lu 177 Dotatate PRRT vs CAPTEM 1 E Total Registrations   2 2 1 0 0 0 06/08/2023 58 25
            2 2 1 0 0 0      
 
  A022004-Colon, Stg II-III, Encor+Cetux vs SOC 0 E Total Registrations   3 3 3 3 1 0 03/06/2024   2
            3 3 3 3 1 0      
 
  A022102-Gastric, FOLFIRINOX +/-Nivo vs FOLFOX +/ Nivo 1 E Total Registrations   10 10 6 5 2 1 05/15/2023 187 82
            10 10 6 5 2 1      
 
  A022104-Rectal, Loc Adv, Triplet vs Doublet Chemo 1 E Total Registrations   51 49 36 17 4 1 03/13/2023 320 126
            51 49 36 17 4 1      
 
  EA2174-Esoph, Peri-Op Nivolumab +/- Ipilimumab 1 E Total Registrations   6 0 0 0 0 0 06/01/2021 222 90
            6 0 0 0 0 0      
 
    2 E Total Registrations   3 0 0 0 0 0 06/01/2021    
            3 0 0 0 0 0      
 
  EA2192-Panc, APOLLO 0 E Total Registrations   4 3 1 0 0 0 12/07/2022 145 84
            4 3 1 0 0 0      
 
    1 E Total Registrations   2 2 1 0 0 0 12/07/2022    
            2 2 1 0 0 0      
 
  NRGGI008-Colon, Stg III, Adj Chemo 1 E Total Registrations   27 21 8 6 2 0 12/08/2022 408 171
            27 21 8 6 2 0      
 
    2 E Total Registrations   17 14 5 3 2 0 12/08/2022    
            17 14 5 3 2 0      
 
No EA2176-Anal, Met, Immune Check Pt Inhibition + Chemo 1 E Total Registrations   28 11 6 4 3 1 08/09/2021 205 86
            28 11 6 4 3 1      
 
  EA2182-Anal, Erly, DECREASE 0 E Total Registrations   12 6 0 0 0 0 05/04/2022 291 96
            12 6 0 0 0 0      
 
    1 E Total Registrations   13 6 0 0 0 0 05/04/2022    
            13 6 0 0 0 0      
 
  EA2197-Gal, Rando Perioperative TX 1 E Total Registrations   5 3 1 0 0 0 11/18/2021 117 70
            5 3 1 0 0 0      
 
  NRGGI004-Colorectal, Stg IV, dMMR Immuno-Therapy 1 Y Total Registrations   15 0 0 0 0 0 04/18/2018 318 114
            15 0 0 0 0 0      
 
  NRGGI005-COLON,Stg IIA, ctDNA in Adjuvant Chemotherapy 1 Y Total Registrations   35 2 0 0 0 0 07/06/2020 429 161
            35 2 0 0 0 0      
 

19-APR-2024 6:10

GI Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs		 # of
CURR
IRBs
A022004 Colon, Stg II-III, Encor+Cetux vs SOC 1 Registration 30-May-23   2
NRGGI008 Colon, Stg III, Adj Chemo 3 Randomization 10-Mar-22 408 171