31-DEC-2025 6:10

GI ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support
STUDY R
E
G
O
P
E
N
ARM ACCR.
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
SWOG S1922-Small Bowel,Ram+Pac vs FOLFIRI, mets/unresect 1 Y 1 Ramucirumab + Paclitaxel 54 23 3 1 0 0 0 06/01/2020 198 56
        2 FOLFIRI   22 2 2 1 0 0      
            45 5 3 1 0 0      
 
  S2104-Panc,Resect High-risk,Postop Adj Chemo vs Obs 1 Y 1 Capecitabine Temozolomide 154 55 19 8 3 2 1 05/05/2022 240 75
        2 Observation   31 11 5 2 1 0      
            86 30 13 5 3 1      
 
  S2303-Gas/Esoph/GEJ, Adv, Ram + Pac +/- Nivo 1 Y 1 Nivolumab + Paclitaxel + Ramucirumab 224 35 29 15 10 3 1 06/24/2024 271 92
        2 Paclitaxel + Ramucirumab   39 32 18 11 2 0      
            74 61 33 21 5 1      
 
Yes A021806-Pancreas, Perioperative vs Adjuvant Chemo 0 E Total Registrations   46 9 5 4 0 0 10/08/2020 286 110
            46 9 5 4 0 0      
 
    1 E Total Registrations   37 6 4 3 0 0 10/08/2020    
            37 6 4 3 0 0      
 
  A022102-Gastric, FOLFIRINOX +/-Nivo vs FOLFOX +/ Nivo 1 E Total Registrations   36 10 6 3 0 0 05/15/2023 237 99
            36 10 6 3 0 0      
 
  EA2174-Esoph, Peri-Op Nivolumab +/- Ipilimumab 1 E Total Registrations   6 0 0 0 0 0 06/01/2021 262 85
            6 0 0 0 0 0      
 
    2 E Total Registrations   3 0 0 0 0 0 06/01/2021    
            3 0 0 0 0 0      
 
  EA2192-Panc, APOLLO 0 E Total Registrations   9 2 1 1 1 1 12/07/2022 156 76
            9 2 1 1 1 1      
 
    1 E Total Registrations   6 2 0 0 0 0 12/07/2022    
            6 2 0 0 0 0      
 
  NRGGI008-Colon, Stg III, Adj Chemo 1 E Total Registrations   67 26 20 10 2 1 12/08/2022 517 203
            67 26 20 10 2 1      
 
    2 E Total Registrations   50 23 16 7 3 1 12/08/2022    
            50 23 16 7 3 1      
 
    3 E Total Registrations   1 1 1 1 0 0 12/08/2022    
            1 1 1 1 0 0      
 
No A022101-Colorectal, Metastatic, Ablative Tx 0 E Total Registrations   2 1 0 0 0 0 07/12/2024 143 64
            2 1 0 0 0 0      
 
    1 E Total Registrations   1 1 0 0 0 0 07/12/2024    
            1 1 0 0 0 0      
 
  CCTGCO32-Rectal, Early Stg, Neoadj/Exc/Obs vs ChemRad 1 E Total Registrations   8 5 1 0 0 0 06/26/2024 177 55
            8 5 1 0 0 0      
 
  CCTGNE1-Midgut NET, Unresect, 177 Lut vs Ever 1 E Total Registrations   6 2 2 2 1 0 06/11/2024 62 19
            6 2 2 2 1 0      
 
  EA2222-Colorectal, Stg II-III, Hep Art Infusion 1 E Total Registrations   6 4 2 0 0 0 06/12/2024 109 42
            6 4 2 0 0 0      
 
  NRGGI004-Colorectal, Stg IV, dMMR Immuno-Therapy 1 Y Total Registrations   15 0 0 0 0 0 04/18/2018 304 101
            15 0 0 0 0 0      
 
  NRGGI005-COLON,Stg IIA, ctDNA in Adjuvant Chemotherapy 1 Y Total Registrations   35 0 0 0 0 0 07/06/2020 424 149
            35 0 0 0 0 0      
 
  NRGGI006-Esophagus, Stg I-IVA, PBT vs IMRT 1 E Total Registrations   1 0 0 0 0 0 06/21/2024 89 34
            1 0 0 0 0 0      
 
    2 E Total Registrations   1 0 0 0 0 0 06/21/2024    
            1 0 0 0 0 0      
 

31-DEC-2025 6:10

GI Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs
# of
CURR
IRBs
S2433 PANC, KRAS WT, Met, SOC Chemo +/- Panitumumab 1 Randomization 26-Dec-25