18-APR-2026 6:10

GI ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support
STUDY R
E
G
O
P
E
N
ARM ACCR.
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
SWOG S1922-Small Bowel,Ram+Pac vs FOLFIRI, mets/unresect 1 Y 1 Ramucirumab + Paclitaxel 54 23 2 0 0 0 0 06/01/2020 203 54
        2 FOLFIRI   23 3 2 1 0 0      
            46 5 2 1 0 0      
 
  S2104-Panc,Resect High-risk,Postop Adj Chemo vs Obs 1 Y 1 Capecitabine Temozolomide 154 61 21 9 6 4 0 05/05/2022 218 72
        2 Observation   33 7 4 2 0 0      
            94 28 13 8 4 0      
 
  S2303-Gas/Esoph/GEJ, Adv, Ram + Pac +/- Nivo 1 Y 1 Nivolumab + Paclitaxel + Ramucirumab 224 46 33 17 10 3 1 06/24/2024 262 88
        2 Paclitaxel + Ramucirumab   45 31 12 5 2 0      
            91 64 29 15 5 1      
 
Yes A022102-Gastric, FOLFIRINOX +/-Nivo vs FOLFOX +/ Nivo 1 E Total Registrations   38 11 5 1 1 0 05/15/2023 245 100
            38 11 5 1 1 0      
 
  EA2174-Esoph, Peri-Op Nivolumab +/- Ipilimumab 1 E Total Registrations   6 0 0 0 0 0 06/01/2021 272 82
            6 0 0 0 0 0      
 
    2 E Total Registrations   3 0 0 0 0 0 06/01/2021    
            3 0 0 0 0 0      
 
  EA2192-Panc, APOLLO 0 E Total Registrations   9 1 1 0 0 0 12/07/2022 163 76
            9 1 1 0 0 0      
 
    1 E Total Registrations   6 1 0 0 0 0 12/07/2022    
            6 1 0 0 0 0      
 
  NRGGI008-Colon, Stg III, Adj Chemo 1 E Total Registrations   79 35 19 11 5 1 12/08/2022 524 199
            79 35 19 11 5 1      
 
    2 E Total Registrations   60 28 16 8 2 0 12/08/2022    
            60 28 16 8 2 0      
 
    3 E Total Registrations   1 1 1 0 0 0 12/08/2022    
            1 1 1 0 0 0      
 
No A022101-Colorectal, Metastatic, Ablative Tx 0 E Total Registrations   2 0 0 0 0 0 07/12/2024 175 68
            2 0 0 0 0 0      
 
    1 E Total Registrations   1 0 0 0 0 0 07/12/2024    
            1 0 0 0 0 0      
 
  CCTGCO32-Rectal, Early Stg, Neoadj/Exc/Obs vs ChemRad 1 E Total Registrations   12 8 4 4 1 0 06/26/2024 177 57
            12 8 4 4 1 0      
 
  CCTGNE1-Midgut NET, Unresect, 177 Lut vs Ever 1 E Total Registrations   7 3 3 1 0 0 06/11/2024 61 19
            7 3 3 1 0 0      
 
  EA2222-Colorectal, Stg II-III, Hep Art Infusion 1 E Total Registrations   7 4 1 1 0 0 06/12/2024 116 40
            7 4 1 1 0 0      
 
  EA2234-Gastric, all stg, Pac+Sys vs Sys 0 E Total Registrations   1 1 1 1 0 0 03/04/2026 153 49
            1 1 1 1 0 0      
 
    1 E Total Registrations   1 1 1 1 1 0 03/04/2026    
            1 1 1 1 1 0      
 
  NRGGI004-Colorectal, Stg IV, dMMR Immuno-Therapy 1 Y Total Registrations   15 0 0 0 0 0 04/18/2018 313 102
            15 0 0 0 0 0      
 
  NRGGI005-COLON,Stg IIA, ctDNA in Adjuvant Chemotherapy 1 Y Total Registrations   35 0 0 0 0 0 07/06/2020 440 150
            35 0 0 0 0 0      
 
  NRGGI006-Esophagus, Stg I-IVA, PBT vs IMRT 1 E Total Registrations   1 0 0 0 0 0 06/21/2024 88 34
            1 0 0 0 0 0      
 
    2 E Total Registrations   1 0 0 0 0 0 06/21/2024    
            1 0 0 0 0 0      
 

18-APR-2026 6:10

GI Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs
# of
CURR
IRBs
S2433 PANC, KRAS WT, Met, SOC Chemo +/- Panitumumab 1 Randomization 26-Dec-25 140 42