16-NOV-2025 6:10

ERLYTX ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support		 STUDY R
E
G		 O
P
E
N		 ARM ACCR.
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
SWOG S2012-Extrapulm NEC, Stg IV, Combo Chemo +/- Atezo 1 Y 1 Platinum/Etoposide + Atezo Induction + Maintenance 189 47 24 11 5 2 1 06/28/2022 254 77
        2 Platinum/Etoposide + Atezo Induction   41 20 9 7 2 0      
        3 Platinum/Etoposide Only   41 21 11 6 2 1      
            129 65 31 18 6 2      
 
  EAY191-S3-ComboMATCH: Adv Solid Tumors, Pac+Ipatasertib 1 Y 1 Paclitaxel + Ipatasertib 33 32 28 10 3 0 0 09/22/2023 203 66
            32 28 10 3 0 0      
 
Yes A071401-Prog Meningiomas,SMO/AKT/NF2 Inhib 0 E Total Registrations   52 4 2 2 0 0 02/22/2016 272 82
            52 4 2 2 0 0      
 
    1 E Total Registrations   9 1 1 1 0 0 02/22/2016    
            9 1 1 1 0 0      
 
No AGCT1531-Mult, Stg I-IV, Carbo vs Cisp, Ped &Adult 1 E Total Registrations   4 2 1 1 0 0 10/07/2021 197 114
            4 2 1 1 0 0      
 
  EAY191-ComboMATCH 1 E Total Registrations   21 11 7 3 1 0 08/03/2023 334 125
            21 11 7 3 1 0      
 

16-NOV-2025 6:10

ERLYTX Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs		 # of
CURR
IRBs
AGCT1531 Mult, Stg I-IV, Carbo vs Cisp, Ped &Adult 2 Late Randomization Callback 08-May-17 197 114
EAY191 ComboMATCH 2 Re-Screening 06-Mar-23 334 125