19-APR-2024 6:10

ERLYTX ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support		 STUDY R
E
G		 O
P
E
N		 ARM ACCR.
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
SWOG S2012-Small Cell NEC, Stg IV, Combo Chemo +/- Atezo 1 Y 1 Platinum/Etoposide + Atezo Induction + Maintenance 189 18 15 10 6 3 1 06/28/2022 179 71
        2 Platinum/Etoposide + Atezo Induction   13 9 4 1 0 0      
        3 Platinum/Etoposide Only   12 9 5 2 0 0      
            43 33 19 9 3 1      
 
  EAY191-S3-ComboMATCH: Adv Solid Tumors, Pac+Ipatasertib 1 Y 1 Paclitaxel + Ipatasertib 33 1 1 0 0 0 0 09/22/2023 180 60
            1 1 0 0 0 0      
 
Yes A071401-Prog Meningiomas,SMO/AKT/NF2 Inhib 0 E Total Registrations   44 2 1 1 0 0 02/22/2016 246 90
            44 2 1 1 0 0      
 
    1 E Total Registrations   8 0 0 0 0 0 02/22/2016    
            8 0 0 0 0 0      
 
  EAY191A3-ComboMATCH-RAS-Mutant, All Stg, Palbo+Benim 1 E Total Registrations   2 2 2 2 0 0 02/08/2024 77 27
            2 2 2 2 0 0      
 
No AGCT1531-Mult, Stg I-IV, Carbo vs Cisp, Ped &Adult 1 E Total Registrations   2 1 0 0 0 0 10/07/2021 179 116
            2 1 0 0 0 0      
 
  EAY191-ComboMATCH 1 E Total Registrations   8 8 5 5 1 0 08/03/2023 255 107
            8 8 5 5 1 0      
 
  EAY191E4-ComboMATCH-Pr. Tax-Tx Tumors, Pac+Nilotinib 1 E Total Registrations   3 3 1 0 0 0 08/17/2023 133 57
            3 3 1 0 0 0      
 

19-APR-2024 6:10

ERLYTX Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs		 # of
CURR
IRBs
AGCT1531 Mult, Stg I-IV, Carbo vs Cisp, Ped &Adult 2 Late Randomization Callback 08-May-17 179 116
EAY191 ComboMATCH 2 Re-Screening 06-Mar-23 255 107
EAY191A3 ComboMATCH-RAS-Mutant, All Stg, Palbo+Benim 2 Cohort Migration 15-Nov-23 77 27