08-AUG-2025 6:10

ERLYTX ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support		 STUDY R
E
G		 O
P
E
N		 ARM ACCR.
GOAL		 TOTAL
REGS.		 REGS.
LAST
12
Month		 REGS.
LAST
6
Month		 REGS.
LAST
3
Month		 REGS.
LAST
30
DAYS		 REGS.
LAST
7
DAYS		 DATE OF
FIRST
REG.		 # of
ACT.
INSTs		 # of
CURR
IRBs
SWOG S2012-Extrapulm NEC, Stg IV, Combo Chemo +/- Atezo 1 Y 1 Platinum/Etoposide + Atezo Induction + Maintenance 189 42 23 11 6 2 1 06/28/2022 252 83
        2 Platinum/Etoposide + Atezo Induction   34 16 7 3 0 0      
        3 Platinum/Etoposide Only   34 17 9 4 1 0      
            110 56 27 13 3 1      
 
  EAY191-S3-ComboMATCH: Adv Solid Tumors, Pac+Ipatasertib 1 Y 1 Paclitaxel + Ipatasertib 33 28 24 17 7 6 0 09/22/2023 205 72
            28 24 17 7 6 0      
 
Yes A071401-Prog Meningiomas,SMO/AKT/NF2 Inhib 0 E Total Registrations   50 3 1 0 0 0 02/22/2016 260 81
            50 3 1 0 0 0      
 
    1 E Total Registrations   8 0 0 0 0 0 02/22/2016    
            8 0 0 0 0 0      
 
  EAY191A3-ComboMATCH-RAS-Mutant, All Stg, Palbo+Benim 1 E Total Registrations   2 0 0 0 0 0 02/08/2024 230 83
            2 0 0 0 0 0      
 
No AGCT1531-Mult, Stg I-IV, Carbo vs Cisp, Ped &Adult 1 E Total Registrations   3 1 1 0 0 0 10/07/2021 182 112
            3 1 1 0 0 0      
 
  EAY191-ComboMATCH 1 E Total Registrations   18 8 7 4 1 1 08/03/2023 305 120
            18 8 7 4 1 1      
 
  EAY191A6-ComboMATCH: MAPK Tumors, Adv Stg, FOLFOX+Bin 1 E Total Registrations   2 1 1 1 0 0 07/18/2024 212 79
            2 1 1 1 0 0      
 

08-AUG-2025 6:10

ERLYTX Open Studies with No Registrations

Study Registration/Phase Open Date # of
ACT.
INSTs		 # of
CURR
IRBs
AGCT1531 Mult, Stg I-IV, Carbo vs Cisp, Ped &Adult 2 Late Randomization Callback 08-May-17 182 112
EAY191 ComboMATCH 2 Re-Screening 06-Mar-23 305 120
EAY191A3 ComboMATCH-RAS-Mutant, All Stg, Palbo+Benim 2 Cohort Migration 15-Nov-23 230 83