31-DEC-2025 6:10

BREAST ACCRUAL REPORT - Open and Recently Closed Studies

SWOG/
Support
STUDY R
E
G
O
P
E
N
ARM ACCR.
GOAL
TOTAL
REGS.
REGS.
LAST
12
Month
REGS.
LAST
6
Month
REGS.
LAST
3
Month
REGS.
LAST
30
DAYS
REGS.
LAST
7
DAYS
DATE OF
FIRST
REG.
# of
ACT.
INSTs
# of
CURR
IRBs
SWOG S2206-Brst, Stg II-III, MP2, Neoadj Chemo +/- Durva 1 Y 1 Tissue for MammaPrint testing 960 826 527 244 132 31 6 11/27/2023 397 135
            826 527 244 132 31 6      
 
    2 Y 2 SOC Chemotherapy   146 100 47 25 6 0 11/27/2023    
        3 SOC Chemotherapy + Durvalumab   144 98 47 28 7 0      
            290 198 94 53 13 0      
 
  S2212-Breast, TNBC, Neoadj Chemo + Pembro 1 Y 1 Carbo + Paclitaxel + Pembro -> AC + Pembro 2400 537 323 176 88 24 2 09/15/2023 413 157
        2 Carbo + Docetaxel + Pembro   537 321 171 86 26 3      
            1074 644 347 174 50 5      
 
Yes A011801-BRST, HER2+, T-DM1+Placebo v T-DM1+Tucatinib 1 E Total Registrations   55 4 0 0 0 0 03/11/2021 453 207
            55 4 0 0 0 0      
 
  A012103-Breast,StgT1cN1-2/T2-4N0-2,obsvsPembrolizumab 1 E Total Registrations   46 32 15 8 1 0 08/24/2023 420 186
            46 32 15 8 1 0      
 
  MA39-BREAST, Node-Pos, Reg RT vs No Reg RT 1 E Total Registrations   69 26 10 6 4 0 10/18/2019 422 159
            69 26 10 6 4 0      
 
    2 E Total Registrations   66 24 9 5 3 0 10/18/2019    
            66 24 9 5 3 0      
 
  NRGBR002-Brst, OMBC, II-III, SoC +/- SBRT and/or SA 1 T Total Registrations   1 0 0 0 0 0 09/22/2017 6 2
            1 0 0 0 0 0      
 
  NRGBR005-Br, Stg II&IIIA, Post NAdj Chemo Br Conserv 1 T Total Registrations   7 0 0 0 0 0 06/22/2018    
            7 0 0 0 0 0      
 
No A012301-Breast, Early Stg, Tamoxifen 1 E Total Registrations   56 56 50 40 12 1 03/07/2025 428 152
            56 56 50 40 12 1      
 
  NRGBR007-Breast, Stg I, De-Escalation of Breast RT 1 E Total Registrations   33 16 8 3 1 0 06/01/2022 423 173
            33 16 8 3 1 0      
 
    2 E Total Registrations   31 15 8 3 1 0 06/01/2022    
            31 15 8 3 1 0      
 
  NRGBR009-Breast, EarlyStg, Adjuvant Chemo 1 E Total Registrations   36 28 21 16 5 0 01/31/2024 482 195
            36 28 21 16 5 0      
 
    2 E Total Registrations   31 23 16 12 3 0 01/31/2024    
            31 23 16 12 3 0